An epistemic logic is built up on the basis of an analysis of two skeptical arguments. the method used is to first construct an inference relation appropriate to epistemic contexts and introduce "a knows that..." as an operator giving rise to sentences closed with respect to this new concept of inference. soundness and completeness proofs are provided using auxiliary three-valued valuations.

The purpose of this article is to comprehensively review studies that have examined the relation between diet and childhood obesity. The review specifically considers the roles of total energy intake and energy density; dietary composition; individual foods, food groups, and dietary patterns; beverage consumption; and eating behaviors. The paper also discusses methodological considerations and future research directions and concludes by summarizing the evidence presented and highlighting the ethical issues surrounding providing dietary advice.

Desmosomes are junctions involved in intercellular adhesion of epithelial cells and hemidesmosomes are junctions involved in adhesion of epithelia to basement membranes. Both are characterised at the ultrastructural level by dense cytoplasmic plaques which are linked to the intermediate filament cytoskeleton of the cells. The plaques strongly resemble each other suggesting a relationship between the two kinds of junctions, as implied by their names. Recent characterisation of the molecular components of the junctions shows they are, in fact, quite unrelated implying (...) that structural similarity is fortuitous. The molecular biology raises many fascinating problems relating to their structure and function. (shrink)

Childhood obesity is a serious problem for increasing numbers of children around the world. According to the International Obesity Task Force, 1 of 10 schoolaged children worldwide is overweight or obese, a number totaling 155 million; of these, 2-3% are obese. Prevalence is highest in the Americas and Europe, followed by the Near/Middle East, with smaller but growing numbers in the Asia-Pacific and Sub-Saharan regions of the world.In the United States, which provides the data for much of this report, prevalence (...) continues to rise. The most recent nationally representative data indicate that 33.6% of individuals aged 2-19 years were overweight and 17.1% were at risk for overweight in 2003-2004, compared to 28.2% and 13.9% in 1999-2000, respectively. In this age group, the prevalence of overweight or at risk for overweight was highest among Mexican Americans, followed by Non-Hispanic blacks and Non-Hispanic whites, and a higher percentage of males were overweight compared to females. (shrink)

Using covariant derivatives and the operator definitions of quantum mechanics, gauge invariant Proca and Lehnert equations are derived and the Lorenz condition is eliminated in U(1) invariant electrodynamics. It is shown that the structure of the gauge invariant Lehnert equation is the same in an O(3) invariant theory of electrodynamics.

Scientists in many fields are presently giving the closest attention to study of the potentials of the systems approach for understanding what cannot be comprehended with the analytical approach or, as V. A. Engel'gardt has put it, "an accumulation of material in reduced form." This approach is in some degree a gesture of despair. It is quite obvious that we now face the danger of drowning in the abundance of data accumulated in terms of "special" problems not tied into a (...) system, and that this threatens loss of general direction. (shrink)

It would be difficult to name a more interesting scientific problem than that of knowledge of the brain, its overall mechanisms and its molecular nature. Rational management of the brain in the future and utilization of the principles of its functioning to construct various mechanisms to undergird present-day technological progress should follow as direct consequences of development of that sphere of knowledge.

A Principle of fundamental importance, if it is valid, for the interpretation of the Pentekontaetia is laid down by the authors of A. T.L. iii in its most rigorous terms: it is that Thucydides has set events ‘in proper order … without any deviation whatever’. The conclusion appears to the present writer to be founded ultimately on a false assumption about Thucydides' purpose in these chapters, namely that he set out to write an outline history of the period of fifty (...) years to which he refers in 118.2 and, in effect, in 97. An examination of these passages reveals that it is not the outline of a period as a period that is offered, but rather the account of a particular theme or process falling within the period: his purpose in presenting the theme there defined is to be seen from the setting of the excursus as a unit in Bk. I rather than from the statement in 97.2: the due significance of this last, and of the demarcation of a period in 118. 2, is to be seen only in this wider context. (shrink)

Uneasy times such as the present are distinguished by the extreme indeterminacy and fuzziness of the language they use. But as a rule this is veiled over, not unsuccessfully, if often unconsciously and with self-deception. The concrete examples or "figures" of linguistic expression are quite diverse: they include the reduction of the conceptual structures of language to purely verbal constructions and schemata, the uncommonly frequent use of certain words and expressions, which creates the illusion that they are clear and well (...) defined, and much, much else. (shrink)

Pluralism is on everyone's lips these days. Only lazy people do not refer to it. Politicians and authorities on political affairs are particularly eager to talk about it. Not to be left behind are scholars who broaden pluralism to a philosophical methodological position that fits best the spirit of the times and the present historical situation. Some writers view pluralism as the most important discovery of the twentieth century, a further development of the Copernican revolution in philosophy.